Prevention strategy in India
Effective and safe interventions for prevention of malaria in pregnancy in India: an assessment of burden of malaria in pregnancy, the efficacy and implementability of a screening strategy and barriers to scaling up interventions.
The study aimed to determine the efficacy and implementability of intermittent screening and treatment (IST) compared to passive case detection and management (PCD) on the risk of placental malaria and its consequences. This was a cluster randomized, controlled trial with two arms undertaken among pregnant women of all parities. The control arm saw women symptoms being tested for malaria, while in the intervention arm all women were tested. If positive women were treated with artesunate (AS) and sulphadoxine pyremithamine (SP). The blood of all women was taken and examined.
Principal Investigators: Dr Neena Valecha (India) and Prof Daniel Chandramohan (UK)
Co-Principal investigators: Dr Anupkumar Anvikar (India) and Prof Feiko ter Kuile (UK)
Dr Neelima Mishra (Rourkela, India), Dr B Shahi (Ranchi, India), Ms I Kupfer (UK), C Drakeley (UK) Ms J Bruce, Ms J Webster (UK), Prof B Greenwood (UK)
Available data on the epidemiology of MiP, and efficacy, safety and cost-effectiveness of potential interventions to control MiP in India are inadequate to recommend evidence based policies. Thus, we propose to generate the information needed to develop an evidence-based, effective national MiP control programme.