Prevention strategy in India

Effective and safe interventions for prevention of malaria in pregnancy in India: an assessment of burden of malaria in pregnancy, the efficacy and implementability of a screening strategy and barriers to scaling up interventions.

Project Coordinators:            Dr Neena Valecha (India) and Prof Daniel Chandramohan (UK) 

Co-Principal investigators:  Dr Anupkumar Anvikar (India) and Prof Feiko ter Kuile (UK)

Project Collaborators: 
Dr Neelima Mishra (Rourkela, India), Dr B Shahi (Ranchi, India), Ms I Kupfer (UK), C Drakeley (UK) Ms J Bruce, Ms J Webster (UK), Prof B Greenwood (UK)


Objective:

The study aimed to determine the efficacy and implementability of intermittent screening and treatment (IST) compared to passive case detection and management (PCD) on the risk of placental malaria and its consequences. This was a cluster randomized, controlled trial with two arms undertaken among pregnant women of all parities. The control arm saw women symptoms being tested for malaria, while in the intervention arm all women were tested. If positive women were treated with artesunate (AS) and sulphadoxine pyremithamine (SP). The blood of all women was taken and examined.